CCL2 and Huntington disease: S-CNS patients also produced significantly elevated levels of the chemokines CCL2 (monocyte chemoattractant protein-3 [MCP-1], CCL3 (macrophage inflammatory protein-1α [MIP-1α]), CCL7 (monocyte chemoattractant protein-3 [MCP-3]), and CCL19 (macrophage inflammatory protein-3β [MIP-3β]), compared to HD (Fig 5i–5l).