MKI67 and central nervous system cancer: After 72 hours, treatment with BafA1 significantly decreased glioma proliferation (Ki67 labelling; p = 0.02; Figure 6A, 6B) and induced apoptosis (cleaved Caspase-3Asp175 expression; p = 0.03; Figure 6A, 6C) while TMZ had little effect (Figure 6A-6C).