Cell motility of LN229 cells after ATP6V1G1 knock-down was modestly impaired (Supplementary Figure 9G, 9H), with a reduction of invaded cells of about 30% (Supplementary Figure 9H), whereas cell invasion was not impaired by V1G1 depletion in differentiated GBM cultures (Supplementary Figure 9I). The gene discussed is ATP6V1G1; the disease is glioblastoma.