ITGAM and parasitic infectious disease: The resistance of these animals results from their capacity to develop IFN-γ and MyD88-dependent CD11b+ myeloid cells, i.e. M1-type myeloid cells, including CCR2-dependent Ly6C+ monocytes and macrophages that secrete trypanotoxic molecules like TNF and NO and exert phagocytic activity to control the parasitemia [3–9].