CD14 and chronic obstructive pulmonary disease: This finding indicates that, despite baseline differences in certain variables (i.e., history of myocardial infarction and COPD) and in other potential confounders (age, gender, BMI and type of infection: gram-negative, gram-positive and fungal), the CD14 rs2569190 C allele remained a prognostic variable with a significant effect on the short-term outcome (30-day survival) in our cohort of sepsis patients (Table 3).