Although the overall probabilities of PTC for thyroid nodules with MN US and FNAB findings were almost 100% (HR US, 98.7%; SM FNAB, 99.0%; MN FNAB, 99.2%, respectively), the probabilities of PTC according to each diagnostic parameter for US and FNAB were different according to BRAF mutation status. Here, BRAF is linked to thyroid nodule.