Results from this analysis showed that SNPs in TCF21 peaks have significantly greater LD than expected by chance with SNPs for CAD related phenotypes: CAD (permutation P = 0.0209) and for CAD Extended (permutation P = 0.0086) that analyzed GWAS SNPs plus those from CARDIoGRAM+C4D (Table 5 and Fig 3). The gene discussed is TCF21; the disease is coronary artery disorder.