Shown here are TCF21 peak regions in three genes that have been identified as replicated CAD GWAS loci, IL6R, SH2B3, and SMG6. Due to this overlap, as well as the similarities in peak binding patterns described above, we intersected the two datasets to refine the number of peaks to those identified by both antibodies (Ab_shared, Fig 1B) and, unless otherwise noted, employed this data set for the analyses presented below. The gene discussed is SH2B3; the disease is coronary artery disorder.