In human and mouse cells, Rab18 has been identified in lipid droplets, organelles that store neutral lipids.[1–6] Recent research showed that the mutations in RAB18 gene are correlated to the Warburg micro syndrome and Martsolf syndrome.[6,7] In plants, Rab18 gene over-expression can improve the salt stress, cold stress, freezing stress and drought stress resistance in Arabidopsis thaliana,[8–12] and is also related to Oryza sativa salinity stress response.[13]. The gene discussed is RAB18; the disease is Micro syndrome.