TNF and colorectal carcinoma: CRC patients in stage IV of CRC with GG genotype showed significantly elevated levels of TNF-α compared to all earlier stages of CRC with the same genotype (for stage I: 34.4 ± 4.8 pg/mL, p = 0.042; for the stage II: 34.9 ± 6 pg/mL, p = 0.018; for stage III: 34.4 ± 7 pg/mL, p = 0.013).