TERT and Burkitt lymphoma: This occurs in both EBV-immortalized LCL and fully transformed EBV-positive Burkitt lymphoma (BL) cell lines, thus supporting the concept that TERT is a critical regulator of the balance between EBV latency and lytic replication in B cells.3, 9, 10 The fine mechanisms by which TERT level modulates the expression of EBV lytic proteins are still unclear.