Four LB variants were observed in more than one patient: the synonymous MYLK c.4764G>A was present in three patients (two familial, one sporadic), the synonymous MYLK c.4179C>T and the intronic variant MYH11 c.5635-7G>A occurred in one familial and one sporadic patient, and the missense EFEMP2 p.Gly93ser was present in three patients with familial AAA without evidence of segregation. This evidence concerns the gene MYH11 and triple-A syndrome.