In another study, alginate-enclosed, chitosan-conjugated, calcium phosphate-iron-saturated bovine lactoferrin (Fe-bLf) nanocarriers/nanocapsules (NCs) showed effective internalization and reduction of cancer stem cell markers in triple-positive CD133, survivin and CD44 cancer stem-like cells both in vitro and in vivo. The gene discussed is BIRC5; the disease is cancer.