We next analyzed Trop-2 expression levels in human PCa tissues by immunohistochemistry (IHC) using a Tissue Microarray (TMA) containing 104 cores from stage pT2 (organ-confined) and 44 cores from stages pT3/pT4 (PCa with extracapsular extension) cancer specimens collected from radical prostatectomies (Table 1). The gene discussed is TACSTD2; the disease is posterior cortical atrophy.