Although DMD is caused by frame-disrupting mutations in the DMD gene that prevent the full translation of dystrophin in muscles of DMD patients [5, 6] and in mdx mice – the murine model of DMD [7–9]– both exhibit sporadic low percentages of dystrophin-positive myofibers known as revertant fibers (RFs). This evidence concerns the gene DMD and Duchenne muscular dystrophy.