The detection of many PSMA-positive supradiaphragmatic lymph nodes with [18F]DCFPyL in addition to retroperitoneal lymph node metastases also detected with [68Ga]Ga-PSMA-HBED-CC supported the decision to omit local radiotherapy of the retroperitoneal lymphatic pathways (patient 12). The gene discussed is FOLH1; the disease is metastatic malignant neoplasm in the lymph nodes.