TP53 and neoplasm: In young group, TNM stage, tumour growth pattern, surgical type, recurrence, PRL (hazard ratios, HR = 12.341; 95% confidence intervals, CI = 1.615-94.276; P = 0.010; Supplementary Figure 2a), RBM3 (HR = 0.093, 95% CI = 0.012-0.712, P = 0.018; Supplementary Figure 2b), Wrap53 (HR = 1.952, 95% CI = 0.452-6.342, P = 0.031; Supplementary Figure 2c), p53 (HR = 5.549, 95% CI = 1.176-26.178, P = 0.045; Supplementary Figure 2d) and DNA status (HR = 17.602, 95% CI = 2.551-121.448, P = 0.001; Supplementary Figure 2e) were strongly associated with CSS.