Of 255 acute febrile episodes, experienced by 235 children (7.8% of participants), 50 displayed a 4-fold increase in IgG titer between acute and convalescent samples, or were positive for anti-dengue IgM and were therefore considered as serologically probable dengue cases, and 18 were positive for dengue NS1 antigen and were considered as virologically confirmed dengue cases (Table 2). Here, CD40LG is linked to dengue disease.