Most advanced breast cancers overexpress 4E-BP1 as well [7–9] total and phosphorylated 4E-BP1 (p-4E-BP1) which is highly expressed in high-grade prostatic intraepithelial neoplasia (HGPIN) may help identify patients at a high risk for tumor development [7]. The gene discussed is EIF4EBP1; the disease is neoplasm.