EIF4EBP1 and prostate intraepithelial neoplasia: Most advanced breast cancers overexpress 4E-BP1 as well [7–9] total and phosphorylated 4E-BP1 (p-4E-BP1) which is highly expressed in high-grade prostatic intraepithelial neoplasia (HGPIN) may help identify patients at a high risk for tumor development [7].