Of this, PI3K/AKT is of great importance as it is a major pathway involved in neuroblastoma development [35,36] and was described in primary neuroblastoma cells [37] and other cell lines (including SH-SY5Y, SK-N-SH, SK-N-BE, SK-N-EP and IMR32) [34,35]. Here, AKT1 is linked to neuroblastoma.