Notably, FoxP3- T-bet+ Th1 cells are thought to be the critical source of IL-10 during toxoplasmosis [36], but since previous studies have shown that the AHR is not expressed at detectable levels in Th1 cells it was unlikely that AHR activity would directly affect IL-10 production by this population [37]. The gene discussed is FOXP3; the disease is toxoplasmosis.