However, opposite differences of gene expression ratio between tumor and the adjacent normal tissues were also present, specifically, the gene expression level of UGT1A9 was notably increased in P2-07271 (452.63%, P < 0.001), while that of was significantly decreased in P5-12221 (90.86%, P < 0.001) (Fig 5C). This evidence concerns the gene UGT1A9 and neoplasm.