For example, for 1960–1990 exposure (≥ 75th percentile vs. < 50th percentile), the observed ORs were 1.14 (95% CI: 0.52, 2.49) for tumor TP53-mutation positive cancer, and 1.00 (95% CI: 0.69, 1.44) for tumor TP53-mutation negative cancer. This evidence concerns the gene TP53 and cancer.