To address current gaps in knowledge about the KITL/c-kit signalling pathway in the ovaries of reproductive age women, the specific aims for this study were to characterise the mRNA expression of c-kit and KITL isoforms and to localise c-kit and KITL protein in adult premenopausal human ovarian tissues, including ovarian tissues from women clinically diagnosed PCOS. Here, KIT is linked to polycystic ovary syndrome.