Of the thirty-two candidate genes involved in these pathways, including TLR3, NFκB1, NFκB2, RelA, RelB, TRAF3 and TRAF6, only a SNP in the 5' UTR of the lymphotoxin alpha (LTA; TNF superfamily member 1) was significantly associated with increased risks of cervical and vulvar cancers [103]. The gene discussed is LTA; the disease is vulva cancer.