There have been reports of abnormal protein expression of Prx isoforms in the brains of neurodegenerative diseases such as Alzheimer’s disease (AD), frontotemporal dementia, Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and Huntington’s disease (HD) [53,54,55,56,57]. The gene discussed is PRX; the disease is Huntington disease.