In the present study, the effects of the overexpression of CDX2 on the growth of colon cancer was were investigated via subcutaneous implantation of CDX2-overexpressing LoVo colon cancer cells, delivered using a transfected eukaryotic expression vector, pEGFP-C1-CDX2, into a nude mouse model. Here, CDX2 is linked to malignant colon neoplasm.