Increased expression of BDNF was detected in genistein-treated hippocampus neuronal cells [30], and decreased levels of the miR-223, a hematopoietic-specific microRNA with crucial function in myeloid lineage development, promoting granulocytic and suppressing erythrocytic differentiation, were found in pancreatic cancer cells in response to this isoflavone [31]. The gene discussed is BDNF; the disease is familial pancreatic carcinoma.