TPO and hypothyroidism: Bossowski and Otto-Buczkowska stated that serologically antithyroid antibodies, especially against thyroperoxidase (anti-TPO) and antithyroglobulin (anti-Tg) and more rarely TSH-stimulation blocking antibody (TSBAb), correlate positively with an increased inflammatory reaction in the thyroid and with the development of hypothyroidism [5].