CD4 and tuberculosis: In our study, we observed an increase in CD4+ T cell activation in the Pulmonary-TB-treated group in comparison with the active-pulmonary-TB group and TST+ healthy donors after antigen stimulation (P = 0.016 and P = 0.029, resp., Kruskal-Wallis test followed by Dunn's post hoc test) (Figure 1(c)).