Analogous to the CD4+IFN-γ+ cells, the healthy donors had a significantly higher percentage of antigen-specific CD4+T-bet+ cells than did those with active-pulmonary TB (unstimulated, P = 0.02; antigen, 0.021, Kruskal-Wallis test followed by Dunn's post hoc test), Figure 2(f). Here, CD4 is linked to pulmonary tuberculosis.