Some studies proposed that the infertility in endometriosis patients mainly depends on the impaired ovarian reserve and reduced ovarian response, as indicated by higher FSH, lower anti-Mullerian hormone not detect a significant increase in PRL levels in women with endometriosis, so ruling out hyperprolactinemia as a cause of infertility (12-14). This evidence concerns the gene BRD2 and hyperprolactinemia.