The Wnt pathways, such as wingless-type MMTV integration site family, member 5A (WNT5A), FZD7, casein kinase IIβ (CSNK2B), β-catenin (CTNNB1), CREB-binding protein (CREBBP), and dishevelled-associated activator of morphogenesis 2 (DAAM2), transforming growth factor β (TGFβ), and mitogen-activated protein kinase signaling pathway, have been found to be induced in NPC [35, 38]. The gene discussed is CREBBP; the disease is nasopharyngeal carcinoma.