Among non-gynecological organic etiologies, hormonal abnormalities, autonomic neuropathies (parasympathetic nervous system releases endothelial nitric oxide synthase, ENOS) as complications of DM, along with vascular insufficiency due to atherosclerosis are of most importance.3,4 It seems that somatic sensory system is affected by DM and introits vagina, labia minor and clitoris are the most deteriorated parts of genitalia in diabetic women. The gene discussed is NOS3; the disease is diabetes mellitus.