KDM1A and cancer: Mutations within the N-terminus of LSD1 have been found in different cancers, including A85V in 1 out of 56 cases of nasopharyngeal carcinoma (56), P152T in 1 out of 489 cases of ovarian serous adenocarcinoma (57) and S172A in 1 case of colorectal adenocarcinoma (58).