Moreover, through analysing the SP percentage of tumour formed by injection of miR-148b or Inh-148b PLC/PRF/5 cells, we found that the tumour formed by Inh-148b cells contained 5.29% SP cells, whereas the compared tumour formed by Inh-NC cells only contained 2.44% SP cells; conversely, miR-148b tumour only contained 1.59% SP cells, which was much less than miR-NC tumour contained SP cells (3.10%; Figure 5I), indicating that miR-148b could stimulate the SP cell formation in vivo. The gene discussed is HSPG2; the disease is neoplasm.