- Some cell lines are more representative of the FGFR3-driven tumor pathway (RT112, MGH-U3, 97-7, BC61, RT4, SW-780, and UM-UC-6) whereas others are more representative of the tumor suppressor-driven pathways (5637, 92-1, 96-1, 97-18, 97-24, HT1376, SW-1710, UM-UC-1, UM-UC-13, and VM-CUB-2). This evidence concerns the gene FGFR3 and neoplasm.