EDN1 and idiopathic pulmonary fibrosis: These studies use human cells and tissues from IPF patient lungs; rodent lung models treated with bleomycin or transforming growth factor-β1 (TGF-β1); and rodent primary cultured AEC2s or rat AEC2 cell line RLE-6TN (RLE) cells treated with TGF-β1, endothelin-1 (ET-1), or cultured on fibronectin.