DNAH8 and alternating hemiplegia of childhood: We extend these observations in this large cohort, confirming a similar prevalence among our AHC cases for the 2 most common mutations, and confirming that most mutations causing AHC seem to occur in a region located between the haloacid-dehalogenase-like-hydrolase and the C-terminal-ATPase domains, close to the transmembrane domains of the protein.