For example, vascular endothelial growth factor (VEGF) plays an important role in the pathogenesis of retinal vascular diseases, including exudative (i.e., vascular) age-related macular degeneration (AMD), diabetic macular edema (DME), proliferative diabetic retinopathy and retinopathy of prematurity [1]. This evidence concerns the gene VEGFA and age-related macular degeneration.