IL6 and hemorrhage: In the subgroups with WFNS 1–3 vs WFNS 4, 5, there was a significant difference in the time course of serum IL-6 (logIL-6) levels in relation to outcome at discharge in both subgroups (mild hemorrhage WFNS 1–3, F (1, 20) = 5.08; p = .036; severe hemorrhage WFNS 4, 5, F (1, 21) = 16.85; p = .001), but again the sample size was small (Additional file 4: Figure S4).