ENO1 and neoplasm: The top proteins on the list included vimentin, which is known to have a crucial role in epithelial transformation during invasion and metastasis [35]; Eno-1, which has functions in tumor growth, differentiation, colony formation, and survival [36]; and of HSP-90a/b1 which functions in survival, migration and as a negative regulator involved in proteasomal ubiquitin-dependent protein catabolic processes [36].