PLAAT3 and metastatic neoplasm: Although positive staining of PLA2G16 was present in both non-metastatic and metastatic tumors, the percentage of PLA2G16-positive staining in osteosarcoma with metastases (38/50, 76.0%) was significantly higher than in the samples without metastases (27/69, 39.1%; P<0.01, Table 1).