We observed strong signals for phospho-RPS6 (Ser235/236), phospho-RPS6 (Ser240/244) and phospho-4EBP1 (Thr37/46) in the glioma cell line LNT-229 cultured in DMEM (glucose levels 25 mM) containing 10% serum (Fig 2A and 2B). Here, EIF4EBP1 is linked to central nervous system cancer.