IL4 and gastritis: To understand the effects of flavonoid glycoside and amoxicillin on a H. pylori infected disease, a mouse gastritis model was established using H. pylori. To explore the molecular mechanisms of effects of flavonoid glycoside and amoxicillin on a mouse gastritis model, IFN-gamma, IL-4, gastrin and somatostatin may be the best molecules for the purpose because of the following reasons: H. pylori infection can elevate IFN-gamma-mediated gastric inflammation [43]; IL-4 is an anti-inflammatory and Th2-type cytokine.