UGT1A1 and tuberculosis: In these reported East Asian CNS-II cases, the TB levels of the CNS-II patients increased in the following order with respect to the UGT1A1 variation detected: single variant homozygous Y486D variant, combination heterozygous G71R variant and homozygous Y486D variant, and compound homozygous G71R variant and Y486D variant (144.7 μmol/L, 175.0 μmol/L, and 232.0 μmol/L, respectively).