Pathways important in oncogenesis (pathways in cancer and endometrial cancer), cell adhesion (Axon guidance, Focal adhesion and Gap junctions), cell proliferation (MAPK signaling pathway, Wnt signaling pathway, and cell-cycle), cell survival (TGFβ signaling pathway) and metabolism (GnRH and insulin signaling pathway) were among the pathways enriched by both up and down regulated miRNAs. This evidence concerns the gene INS and endometrial cancer.