To consolidate the association of SIPL1 upregulation (gene copy number increases and mRNA elevation) with BC progression, we have analyzed the relationship between BC patients’ survival with either SIPL1 gene copy number or SIPL1 mRNA levels using the Curtis dataset which contains 816 surviving patients with breast cancer and 429 patients who died from the disease (Table 3). This evidence concerns the gene SHARPIN and breast carcinoma.