PEDF-overexpressing Ex Vivo showed local infiltration from injection site (Fig 7Fb and 7Fd), myelin-associated infiltration in the corpus callosum (Fig 7Ff), and tumor growth at a distance from the injection site (Fig 7Fh) compared with control (Fig 7Fa, 7Fc, 7Fe and 7Fg). This evidence concerns the gene SERPINF1 and neoplasm.