Because CYP1B1 polymorphism (c.1294C>G) was associated with a decreased risk of AML, which contradicts the initial hypothesis, we tested whether the genotypes of CYP1B1, CYP3A4, and CYP3A5 correlate with their own gene expression (S10 Table). This evidence concerns the gene CYP1B1 and acute myeloid leukemia.