TNF and acute respiratory distress syndrome: It is known that inflammatory mediatorsplay an important role in the pathogenesis of severe burn-induced remote ALI.Thus we next examined the mRNA levels of two inflammatory cytokines,TNF-α and IL-1β, in lung tissue after burn injury by qRT-PCR.Results showed that both the mRNA levels of TNF-α (Fig.2D) and IL-1β (Fig. 2E) weresignificantly upregulated by 3 folds when measured at 12 h post-injury,however, this effect was remarkably attenuated by resveratrol treatment (Fig. 2D-E).