While doxorubicin chemotherapy alone was effective in treating metastatic osteosarcoma, p-value = 0.0048, we observed no additional improvement in the survival of mice treated with doxorubicin + α-PD-L1 mAb compared to α-PD-L1 mAb treatment alone (Figure 5). The gene discussed is CD274; the disease is osteosarcoma.