Tumor cells from α-PD-L1 mAb treated mice appeared to have overall slower growth kinetics in vitro, compared to the parental tumor cells, resulting in an overall longer mean survival of ~50 days versus only ~25 days after reimplantation of tumors from untreated mice, which is to be expected as PD-L1 has been shown to speed up tumor cell growth kinetics and provide anti-apoptotic signals [19,20] (Additional file 1: Figure S1). The gene discussed is CD274; the disease is neoplasm.