CD40 and inflammatory bowel disease: Moreover, IBD risk variant rs1569723 is known to act as a cis-eQTL for CD40 (CD40 molecule, TNF receptor superfamily member 5), which was significantly up-regulated in iUC and associated with lncRNA RP11-465 L10.10. Additionally, lncRNA IFNG-ASI harboring UC susceptibility SNP rs7134599 was found to be up-regulated in iUC.