LncRNA RP3-395 M20.8 was found to be associated with the regulatory IBD risk variant rs10797432, which affects the binding motifs for AP-2 (transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)) and CTCF (CCCTC-binding factor (zinc finger protein)) (Table S5 in Additional file 1). This evidence concerns the gene CTCF and inflammatory bowel disease.